It is dedicated to preclinical molecular image research using in vivo image methods such as computed microtomography (microct), positron emission microtomography (micropet) and optical image.

Structure: Micropet/CT, optical image in vivo, gamma counter.

Linhas de pesquisa

• Estudo do metabolismo cerebral in vivo
• Estudos destinados a elucidar os mecanismos de desenvolvimento das doenças e novas alternativas terapêuticas e diagnósticas.

Principais projetos

• Strengthening human resources and capabilities on non-clinical assays of radiopharmaceuticals (IAEA BRA2018003)
• Projeto apoiado pela Agência Internacional de Energia Atômica, e liderado no Brasil pela CNEN/CDTN, cujo objetivo é aprimorar conhecimento e fortalecer recursos humanos para realização de ensaios pré-clínicos de radiofármacos.

Principais artigos

• Clozapine induces astrocyte-dependent FDG-PET hypometabolism, 2022. Acesse aqui
• Targeting FFA1 and FFA4 receptors in cancer-induced cachexia, 2020. Acesse aqui
• Long-term changes in metabolic brain network drive memory impairments in rats following neonatal hypoxia-ischemia, 2020. Acesse aqui
• Depression comorbidity in epileptic rats is related to brain glucose hypometabolism and hypersynchronicity in the metabolic network architecture, 2018. Acesse aqui
• Ketamine promotes increased freezing behavior in rats with experimental PTSD without changing brain glucose metabolism or BDNF, 2017. Acesse aqui