Notícias

News | Research
OCTREO - Production of diagnostic kits Edda Hynic-Toc
RESEARCH PROJECT COMPLETED. Project Coordinator: Cristina Maria Moriguchi Jeckel, PhD Summary of the work: the majority of human neuroendocrine tumors express high density of somatostatin receptors. Through the injection of a somatostatin analog, octreotide, marked with a...
07 de Janeiro de 2019
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Evaluation of Reliability and Reproducibility of Functional Magnetic Resonance Imaging in the Resting State
Project Coordinator: Alexandre Franco, PhD Job Summary: Functional Magnetic Resonance in “Resting-state” (fMRI or rsFMRI), or task-free can assess the intrinsic connectivity of functional networks in healthy and / or troubled brains health, which suggests a potential use of this...
07 de Janeiro de 2019
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Development of different matrices for transplantation of human neural stem cells derived from iPS in trauma
Project Coordinator: Jaderson Costa da Costa, MD, PhD < / p> Members: Daniel Marinovic / Guido Lenz / Cháriston André Dal Belo / Célia Carlini / Asdrubal Falavina / Gianina Teribele / Karolin Ogliari - / Alessandra Sebben / Léder Xavier / Nara Basso / Dénis de Assis / Simone Salamoni...
07 de Janeiro de 2019
$Autologous Bone Marrow Stem Cell Transplantation in Temporal Lobe Epilepsy Refractory to Drug Treatment: Phase II study$
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Autologous Bone Marrow Stem Cell Transplantation in Temporal Lobe Epilepsy Refractory to Drug Treatment: Phase II study
Project Coordinator: Jaderson Costa da Costa, MD, PhD < / p> Members: Ricardo Vaz Breda / Daniela Souza de Abreu / Danielle Irigoyen da Costa / Li Li Min / Zaquer Suzana Munhoz Costa / Fernando Cendes / Alessandra Marques Pereira / Carlos Eduardo Silvado / Eduardo Raupp / Denise Cantarelli...
07 de Janeiro de 2019
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Mechanisms involved in the control of central and peripheral inflammatory response in the experimental model of epilepsy with bone marrow stem cell transplantation
Research Coordinator: Jaderson Costa da Costa, MD, PhD < / p> Summary of the work: Epilepsy is a brain disorder characterized by spontaneous and recurrent attacks of intense, synchronized and rhythmic triggering of neuronal populations. Pronounced inflammatory process has been described in...
07 de Janeiro de 2019
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Neurotoxic activity of ureases and derived peptides
Project Coordinator: Célia Regina R. S. Carlini, PhD Summary of Work: ureases are enzymes produced by plants, bacteria and fungi that hydrolyze urea in ammonia and CO2. In addition to being toxic because they generate ammonia, ureases have other biological properties independent of...
07 de Janeiro de 2019
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Assessment of the permeability of the blood-brain barrier in an experimental model of posterior reversible encephalopathy syndrome through neuroimaging exams
RESEARCH PROJECT COMPLETED. Project Coordinator: Luiz Carlos Porcello Marrone, MD, PhD e Jaderson Costa da Costa, MD, PhD Job Summary: Posterior Reversible Encephalopathy Syndrome ( Posterior Reversible Encephalopathy Syndrome - PRES) is a clinical radiological entity characterized...
07 de Janeiro de 2019
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Effect of umbilical cord blood stem cell transplantation in the treatment of neonatal rats submitted to the germline / intraventricular hemorrhage model
Project Coordinator: Jaderson Costa da Costa, MD, PhD Researcher: Pamella Azevedo, MSc (Project developed during the Masters) Summary of the work: Hemorrhage of the germline / intraventricular matrix (HMG / IV) is the most common neurological complication of newborns, affecting about...
07 de Janeiro de 2019
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Evaluation of the expression modulation of trophic factors after transplantation of bone marrow mononuclear cells in an animal model
Project Coordinator: Jaderson Costa da Costa, MD, PhD Researcher: Gabriele Goulart Zanirati , MSc (PhD Project) < / p> Summary of the work: It is estimated that epilepsy affects about 1% of the world population, with approximately 30% of these patients not responding to drug treatment,...
07 de Janeiro de 2019
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Granulocyte colony-stimulating factor (GCSF) treatment in epilepticus rats
Project Coordinator: Zaquer Suzana Munhoz Costa-Ferro, PhD < / p> Work Summary: In the present study, the effect of G-CSF on recurrent spontaneous seizures (CER) will be evaluated and compared with the effect of mononuclear cells of bone marrow (CMO). The specific objectives are: to...
07 de Janeiro de 2019