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  • Mathematical Modeling in Pharmacokinetics

    News | Research

    Mathematical Modeling in Pharmacokinetics

    Project coordinator: Eliete Biasotto Hauser, PhD Members: Jaderson Costa da Costa, MD, PhD ; Gianina Teribele Venturin, PhD ; Samuel Greggio, PhD The main objective of the project is to use compartment theory as mathematical modeling in the quantification of radiopharmaceutical...

    07 de Janeiro de 2019
  • Test Your Brain - Application to identify the first signs of dementia in the elderly

    News | Research

    Test Your Brain - Application to identify the first signs of dementia in the elderly

    Project Coordinator: Mirna Wetters Portuguez, PhD Members: Sabine Possa Marroni, MSc (PhD Project in progress), Paulo Bertram Garcia, Ingrid Louise and Karen Wolfart Chies. With the advancement of technology, resources with applications are a practical, simple and easy to use option by...

    07 de Janeiro de 2019
  • Electrophysiology and Patch-Clamp: technique to measure electrical activity of isolated ion channels

    News | Research

    Electrophysiology and Patch-Clamp: technique to measure electrical activity of isolated ion channels

    Project Coordinator: Célia Carlini, PhD Invited Researcher: Vitya Vardanyan, PhD , from the Institute of Molecular Biophysics of the Academy of Sciences of the Republic of Armenia The Patch-Clamp is a powerful technique for studying the electrical activity of cells, in particular...

    07 de Janeiro de 2019
  • OCTREO - Production of diagnostic kits Edda Hynic-Toc

    News | Research

    OCTREO - Production of diagnostic kits Edda Hynic-Toc

    RESEARCH PROJECT COMPLETED. Project Coordinator: Cristina Maria Moriguchi Jeckel, PhD Summary of the work: the majority of human neuroendocrine tumors express high density of somatostatin receptors. Through the injection of a somatostatin analog, octreotide, marked with a...

    07 de Janeiro de 2019
  • Evaluation of Reliability and Reproducibility of Functional Magnetic Resonance Imaging in the Resting State

    News | Research

    Evaluation of Reliability and Reproducibility of Functional Magnetic Resonance Imaging in the Resting State

    Project Coordinator: Alexandre Franco, PhD Job Summary: Functional Magnetic Resonance in “Resting-state” (fMRI or rsFMRI), or task-free can assess the intrinsic connectivity of functional networks in healthy and / or troubled brains health, which suggests a potential use of this...

    07 de Janeiro de 2019
  • Development of different matrices for transplantation of human neural stem cells derived from iPS in trauma

    News | Research

    Development of different matrices for transplantation of human neural stem cells derived from iPS in trauma

    Project Coordinator: Jaderson Costa da Costa, MD, PhD < / p> Members: Daniel Marinovic / Guido Lenz / Cháriston André Dal Belo / Célia Carlini / Asdrubal Falavina / Gianina Teribele / Karolin Ogliari - / Alessandra Sebben / Léder Xavier / Nara Basso / Dénis de Assis / Simone Salamoni...

    07 de Janeiro de 2019
  • Autologous Bone Marrow Stem Cell Transplantation in Temporal Lobe Epilepsy Refractory to Drug Treatment: Phase II study

    News | Research

    Autologous Bone Marrow Stem Cell Transplantation in Temporal Lobe Epilepsy Refractory to Drug Treatment: Phase II study

    Project Coordinator: Jaderson Costa da Costa, MD, PhD < / p> Members: Ricardo Vaz Breda / Daniela Souza de Abreu / Danielle Irigoyen da Costa / Li Li Min / Zaquer Suzana Munhoz Costa / Fernando Cendes / Alessandra Marques Pereira / Carlos Eduardo Silvado / Eduardo Raupp / Denise Cantarelli...

    07 de Janeiro de 2019
  • Mechanisms involved in the control of central and peripheral inflammatory response in the experimental model of epilepsy with bone marrow stem cell transplantation

    News | Research

    Mechanisms involved in the control of central and peripheral inflammatory response in the experimental model of epilepsy with bone marrow stem cell transplantation

    Research Coordinator: Jaderson Costa da Costa, MD, PhD < / p> Summary of the work: Epilepsy is a brain disorder characterized by spontaneous and recurrent attacks of intense, synchronized and rhythmic triggering of neuronal populations. Pronounced inflammatory process has been described in...

    07 de Janeiro de 2019
  • Neurotoxic activity of ureases and derived peptides

    News | Research

    Neurotoxic activity of ureases and derived peptides

    Project Coordinator: Célia Regina R. S. Carlini, PhD Summary of Work: ureases are enzymes produced by plants, bacteria and fungi that hydrolyze urea in ammonia and CO2. In addition to being toxic because they generate ammonia, ureases have other biological properties independent of...

    07 de Janeiro de 2019
  • Assessment of the permeability of the blood-brain barrier in an experimental model of posterior reversible encephalopathy syndrome through neuroimaging exams

    News | Research

    Assessment of the permeability of the blood-brain barrier in an experimental model of posterior reversible encephalopathy syndrome through neuroimaging exams

    RESEARCH PROJECT COMPLETED. Project Coordinator: Luiz Carlos Porcello Marrone, MD, PhD e Jaderson Costa da Costa, MD, PhD Job Summary: Posterior Reversible Encephalopathy Syndrome ( Posterior Reversible Encephalopathy Syndrome - PRES) is a clinical radiological entity characterized...

    07 de Janeiro de 2019
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