Alzheimer´s Team

Project Coordinator: Jaderson Costa da Costa, MD, PhD Researchers: Alexandre Rosa Franco, PhD; Ana Maria Marques da Silva, PhD; Celia Ribeiro da Silva Carlini, PhD; Cristina M. Moriguchi Jeckel, PhD; Cristina Sebastião Matushita, MD; Daniel Marinowic, PhD; Diogo Ribeiro Demartini, PhD; Eduardo Zimmer, PhD;Eliete Biasotto Hauser, PhD; Evandro Manica, PhD; Graciane Radaelli, MSc; Leonardo Pisani; Louise Mross ..

Alzheimer´s Team

Pesquisador líder: Jaderson Costa da Costa, MD, PhD; Demais integrantes: Alexandre Rosa Franco, PhD; Ana Maria Marques da Silva, PhD; Celia Ribeiro da Silva Carlini, PhD; Cristina M. Moriguchi Jeckel, PhD; Cristina Sebastião Matushita, MD, MSc; Daniel Marinowic, PhD; Diogo Ribeiro Demartini, PhD; Eduardo Zimmer, PhD; Eliete Biasotto Hauser, PhD; Evandro Manica, PhD; Graciane Radaelli, MSc; Leonardo ..

Emprego do 18F-FDG em PET/CT no sistema único de saúde como alternativa de método não-invasivo para estadiamento e monitoramento terapêutico de câncer de pulmão

Projeto de pesquisa concluído. Coordenador: Dr. Cezar Fritscher Integrantes: Carlos Barrios, PhD; Gustavo Werutsky, PhD; Mara Zanini, PhD; Eduardo Berdichevski, MSc; Vinicius da Silva, PhD; Leandro Fritscher, PhD; Bruno Hochhegger, PhD; Maria Teresa Tsukazan, PhD; Cristina Matushita, MD, MSc; José Pinto, PhD; Laura Voelcker, Raíra Maschmann, Louise Hartman, MSc. O câncer de pulmão é uma ..

Use of 18F-FDG in PET/CT scanners in the unified health system as an alternative to non-invasive methods for the staging and therapy monitoring of lung cancer

Coordinator: Dr. Cezar Fritscher, Researchers: Dr. Carlos Barrios, Dr. Gustavo Werutsky, Prof. Mara Zanini, Dr. Eduardo Berdichevski, Dr. Vinicius da Silva, Dr. Leandro Fritscher, Dr. Bruno Hochhegger, Dr. Maria Teresa Tsukazan, Dr. Cristina Matushita, Dr. José Pinto, Pharmacist Laura Voelcker, Nutritionist Raíra Maschmann, Pharmacist Louise Hartman, Pharmacist Marcos Alba. Lung cancer is a widespread disease ..

Migration assessment and neural differentiation of induced pluripotent stem cells (iPSCs) of patients with cortical dysplasia

Project Coordinator: Jaderson Costa da Costa, MD, PhD Researchers: Daniel Marinowic, PhD Abstract: Cortical Dysplasia is one of the most frequent forms of malformations of cortical development. Changes in cellular traffic are present in several neurological diseases, including refractory epilepsy and dysplasia. Reprogramming of adult somatic cells is a compelling and promising approach because of the possibility ..

Avaliação da migração e neurodiferenciação de células-tronco pluripotentes induzidas (iPS) de pacientes com displasia cortical

Coordenador do Projeto: Jaderson Costa da Costa, MD, PhD Pesquisador: Daniel Marinowic, PhD Resumo do Trabalho: A Displasia Cortical é uma das formas mais frequentes de malformações do desenvolvimento cortical. Alterações no tráfego celular estão presentes em diversas doenças neurológicas, inclusive epilepsia refratária a medicação e displasiasl. A reprogramação de células somáticas adultas é uma abordagem atraente e ..

In-vivo molecular imaging of the migration, distribution and survival of stem cells in an animal model of epilepsy

Project Coordinator: Jaderson Costa da Costa, MD, PhD Research Summary: strategies to promote an increase in the number and function of endogenous regenerative cells, or to introduce cells with regenerative potential in the central nervous system (CNS) may represent important alternatives in the treatment of neurological diseases. Thus, stem cell transplantation arises as a promising ..

Biomarkers in the cognitive continuum of the elderly (CCE): neural networks, functional plasticity and hippocampal volume in older adults in the community

Project Coordinator: André Luis Fernandes Palmini, MD, PhD Research Summary: Advanced age is the main risk factor for degenerative brain diseases. Older adults in the community vary in risk of progression along the cognitive continuum of the elderly (CCE). The project will test senior citizens between 70 and 80 years of age, including educational and ..

Development of Fast and Robust Dynamic MRI Techniques using Compressed Sensing for Evaluation of Cystic Fibrosis

Special Visiting Professor: Ricardo Otazo, PhD (New York University) InsCer Coordinators: Augusto Buchweitz, PhD and Alexandre R. Franco, PhD Research Summary: The project aims to develop and validate fast and motion-robust magnetic resonance imaging techniques, with high spatial and temporal resolution for (a) better assessment of cystic fibrosis patients without the risks of radiation and ..

Evaluation of microglial activation by PET/CT and its association with the appearance of lesions on MRI in patients with relapsing-remitting multiple sclerosis undergoing fingolimode therapy

Project Coordinator: Jefferson Becker, MD, PhD Research Summary: Multiple sclerosis (MS) is the most common inflammatory disease of the central nervous system (CNS), characterized by considerably varying clinical and pathological manifestations. Several pathological studies on Multiple Sclerosis have shown that myelin and its supporting cells, oligodendrocytes, are usually destroyed in MS lesions. White matter lesions ..